Benign and Pathological Chromosomal Imbalances(1st Edition) Microscopic and Submicroscopic Copy Number Variations (CNVs) in Genetics and Counseling by ThomasLiehr Hardcover, 199 Pages, Published 2013 by Academic Pr ISBN-13: 978-0-12-404631-3, ISBN: 0-12-404631-2
"Given technology-driven FISH, aCGH approaches have yet to reach the much-touted promise of universal coverage or cost efficacy to sample investigated, deep chromosome analysis and molecular cytogenetics will remain relevant for technology translation, study design and therapeutic assessment for many years. This book provides a classification system to clarify the disease implications of cytogenetically visible copy number variants usin ..."
Cytogenomics(1st Edition) by ThomasLiehr 408 Pages, Published 2021 by Academic Press ISBN-13: 978-0-12-823579-9, ISBN: 0-12-823579-9
"After an introduction to molecular cytogenetics, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jumpstart their own projects, and more effectively gather ..."
Cytogenomics by ThomasLiehr 408 Pages, Published 2021 by Academic Press ISBN-13: 978-0-12-823580-5, ISBN: 0-12-823580-2
"This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, ..."
Benign and Pathological Chromosomal Imbalances Genetic Diagnostics, Patient Counselling, and Treatment Plan Development by ThomasLiehr Digital, 220 Pages, Published 2013 by Academic Press ISBN-13: 978-0-12-404684-9, ISBN: 0-12-404684-3
"... 21 or 22) 16qhþ 98/39, 612 0.25% Walzer et al., 1969 Bochkov et al., 1974
Nielsen, Friedrich, Areidarsson, 1974 Tu ̈u ̈r et al., 1974 Mikelsaar et al., 1975
Hamerton et al., 1975 Nielsen and Sillesen, 1975 Schwanitz, 1976 87/26, 143
0.33% Walzer et al., 1969 Bochkov et al., 1974 Nielsen, Friedrich, Areidarsson,
Zeuthen, 1974 Mikelsaar et al., 1975 Nielsen and Sillesen, 1975 Schwanitz,
1976 Metaxotou et al., 1978 962/40, 397 2.3 ..."
"This book summarizes applications of cytogenetics and molecular cytogenetics for students, clinicians and researchers in genetics, genomics and diagnostics."
"Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones. This sSMC can originate from any one of the 24 human chromosomes and can have different shapes. Approximately one third of sSMC carriers show clin ..."
Fluorescence In Situ Hybridization(2nd Edition) (FISH): Application Guide (Springer Protocols Handbooks) by ThomasLiehr Hardcover, 606 Pages, Published 2016 by Springer ISBN-13: 978-3-662-52957-7, ISBN: 3-662-52957-2
"This manual offers detailed protocols for fluorescence in situ hybridization (FISH) and comparative genomic hybridization approaches, which have been successfully used to study various aspects of genomic behavior and alterations. Methods using different probe and cell types, tissues and organisms, such as mammalians, fish, amphibians (including lampbrush-chromosomes), insects, plants and microorganisms are described in 57 chapters. In a ..."
FISH Technology(2002nd Edition) (Springer Lab Manuals) by Bernd W. Rautenstrauß, ThomasLiehr Paperback, 494 Pages, Published 2012 by Springer ISBN-13: 978-3-642-47739-3, ISBN: 3-642-47739-9
"Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on native human tissues, such as blood, bone marrow, epithelial cells, hair root cells, amnio ..."
"This book is a unique source of information on the present state of the exciting field of molecular cytogenetics and how it can be applied in research and diagnostics. The basic techniques of fluorescence in situ hybridization and primed in situ hybridization (PRINS) are outlined, the multiple approaches and probe sets that are now available for these techniques are described, and applications of them are presented in 36 chapters by aut ..."
"Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on native human tissues, such as blood, bone marrow, epithelial cells, hair root cells, amnio ..."
"Bernd W. Rautenstrauß, Thomas Liehr. Christian AT, Garcia HE, Tucker JD (1999
) PCR in situ followed by microdissection allows whole chromosome painting
probes to be made ... Nature 365:566-568 Flemming W (1882) Zellsubstanz,
Kern und Zellteilung. Leipzig. Flint J, Wilkie AOM, Buckle VJ, Winter RM, Holland
AJ, McDermid HE (1995) The detection of subtelomeric chromosomal
rearrangements in idiopathic mental retardation. Nat Genet 9:13 ..."
Fluorescence In Situ Hybridization(Softcover reprint of the original 2nd ed. 2017) (FISH): Application Guide (Springer Protocols Handbooks) by Liehr, Thomas Trade Paperback, 619 Pages, Published 2018 by Springer ISBN-13: 978-3-662-57100-2, ISBN: 3-662-57100-5
"This manual offers detailed protocols for fluorescence in situ hybridization (FISH) and comparative genomic hybridization approaches, which have been successfully used to study various aspects of genomic behavior and alterations."
"This book is a unique source of information on the present state of the exciting field of molecular cytogenetics and how it can be applied in research and diagnostics. The basic techniques of fluorescence in situ hybridization and primed in situ hybridization (PRINS) are outlined, the multiple approaches and probe sets that are now available for these techniques are described, and applications of them are pre ..."
"This special issue focuses on the recent developments in the exciting and continuously progressing field of human multicolor fluorescence in situ hybridisation (mFISH), highlighting the advantages, applications and possible limitations of this technique. Today, mFISH assays are indispensable for the precise characterization of complex chromosome rearrangements and numerical chromosome aberrations. In a first, more technically oriented p ..."
"Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones. This sSMC can originate from any one of the 24 human chromosomes and can have different shapes. Approximately one thir ..."